In Devon, 17-year old Ray is about to start his physical transition from female to male. Will the NHS agree to fund surgery for his breasts to be removed?
Desperate to begin physically transitioning, Lee is trapped in a lengthy wait for NHS treatment. Will he ever get his prescription for testosterone?
Simon, who's been married to Julie for 35 years, has decided to live full-time as Jackie. And Cairo has given up a career in modelling - can he return to the job, this time as a male model?
After over 25 years of married life, Pete has come out as a transwoman to his wife; and student Emma is self-prescribing hormones following a lengthy wait for NHS treatment
As high-flying businessman Kevin transitions to Karen, will their professional reputation be put at risk? On a rare trip home, can Andrew convince the family they're no longer Melanie.