Unable to cope with prison life, Macarena is taken under the wing of her cellmate Yolanda. But a midnight visit from Zulema, the jail's self-appointed queen bee, is about to change her life for ever.
Macarena is caught with a package of drugs and is tricked into revealing who owned them. She admits she's in prison to her mother and father and is inspired to tell the truth about Yolanda's murder.
Macarena confronts Zulema and admits she told the warden what she saw on the night of Yolanda's death, putting her family in danger. A routine drugs test is about to turn Macarena's life upside down.
After threats by Macarena's father Leopoldo, her ex-lover runs away with the fraud money. Macarena confides in Leopoldo about Yolanda's missing millions and he urges her to find the stolen SIM card.
Macarena gets a new cellmate and they become great friends. Prison guard Palacios is wrongly accused of sexual impropriety and suspended. Macarena's brother Roman is kidnapped by Zulema's boyfriend.
Prison guard Fabio gets Palacios off the hook. Macarena is caught on tape admitting to possessing the SIM card. The police take Macarena to the forest to find the missing money, but they're not alone.
Macarena has changed her mind about her pregnancy and is happy to be expecting a baby boy. The warden delivers some good news. Zulema is growing increasingly worried about her boyfriend's silence.
Zulema's boyfriend sneaks into Macarena's family home and steals the photos showing the secret location of the stolen millions. Fabio informs Macarena about a betrayal. Zulema gets a secret message.
Macarena's caught smuggling drugs and ends up in debt to the prison doctor, Zulema and her rival Anabel. As Zulema prepares to escape, Leopoldo closes in on her boyfriend and is ready to confront him.
A DNA test could help to prove Macarena's innocence, but the doctor refuses to perform one at this stage in her pregnancy. Macarena asks Fabio to help her, but things don't go as she had planned.
Zulema's escape plans are scuppered when Leopoldo captures her boyfriend, but emergency circumstances force Roman to take matters into his own hands. The prison doctor turns Fabio against Macarena.
Roman is forced to confess everything to his mother, who removes a bullet from the leg of Zulema's boyfriend. Macarena gets into big trouble with the other inmates when a fight results in a broken TV.
Zulema poisons and kidnaps Macarena and also takes Palacios hostage. She insists that unless Leopoldo releases her boyfriend right away, Macarena will lose the baby, but Leopoldo has his own plan.
Macarena is out of the infirmary but the prison doctor wants to transfer her to a psychiatric hospital against her will. Macarena's family has the stolen money but Zulema's boyfriend is after them.
When Zulema's boyfriend takes revenge on Roman's family, Macarena attacks Zulema. Fabio's suspicions are confirmed. DNA samples taken at the time of Macarena's miscarriage prove her ex was lying.
Zulema betrays her boyfriend for money. Roman resolutely seeks revenge. Macarena is about to attend a court hearing that could secure her freedom when she stumbles upon Zulema's latest escape plan.