Roma have received a blow ahead of their must-win game against Sampdoria as influential winger Rodrigo Taddei has been ruled out through injury.
Luciano Spallettis men have faint hopes of the Scudetto, but must take maximum points in their remaining three games and hope for Inter to capitulate.
The Giallorossi face a tough test away to Champions League chasing Sampdoria and the game has been made more daunting by the loss of Taddei.
The Brazilian seemed to strain a thigh muscle during training and is hoping to return for next Thursdays Coppa Italia semi-final second leg against Catania.
Spalletti will have to shuffle the deck and may opt to try Ludovic Giuly or Mauro Esposito in Taddeis place or push Max Tonetto forward from defence and bring Marco Cassetti in.
Inspirational captain Francesco Totti and alleged Milan target Matteo Ferrari are already missing and there are also doubts over the fitness of goalkeeper Alexander Doni and veteran defender Christian Panucci.