Cagliaris hopes of avoiding the drop have been dealt a blow as key striker Robert Acquafresca has picked up a potentially serious injury.
The Azzurrini star, who is co-owned by Inter, has enjoyed an excellent campaign at the Stadio SantElia with nine goals to his name.
In a squad with few striking options, the 20-year-old has become an important figure for Coach Davide Ballardini.
However, Acquafresca limped off against Inter last weekend with a groin problem and early indications suggest that it may be serious enough to rule him out of the final three games.
Cagliari are outside the drop zone at the moment, but they must negotiate Fiorentina and Udinese in their next two games.
Survival may depend on the result of their final game of the season against fellow strugglers Reggina.