Karen is famous across the Chatsworth Estate for her sexual skills as well as for sleeping with Frank while he was dating her mother and she was dating Frank's son Lip.
Karen is the daughter of recovering agoraphobic Sheila, Frank's second wife, and is one of the softer female residents of Chatsworth.
The arrival of Jamie Maguiretamed Karen's wildly sexual ways and she eventually married into the feared family, but only after she endured some severe psychological torture from Maguire matriarch,Mimi.
Karen works in The Jockey and is every inch the reformed slapper. The drama surrounding her pregnancy, the break up with Jamie and her tumultuous relationship with Joe led to a catalogue of mental health problems which her family tried in vain to support her through.
It's early days for Karen and Jamie since getting back together, and who knows what the future holds...