Find out more about the children as they reach the end of early childhood.
Despite Shelbie's condition deteriorating, (including a diagnosis of diabetes), the Patrial Trisomy 9P sufferer still continues to defy the odds, and celebrates her eleventh birthday.
A confident and assured Zoe has not benefitted from the surgery to correct the effects of Arthrogryposis on her left arm as much as it was originally hoped, but chooses to have further surgery on her right arm too.
To cure double incontinence caused by Spina bifida, Emily has had surgery on her bowel and bladder. She is excited at the prospect of no longer having to wear pull-up nappies. As well as being able to go the toilet independently, Emily is able to go on residential school trips with her classmates.
William, who has autism as a result of Tuberous sclerosis, is walking and talking well. He has survived two incidences of major surgery to remove tumours in his brain caused by his illness.
Nathan's parents are pleased with their decision to send their child to a mainstream primary school but feel that his Down's syndrome will be better catered for at secondary level in a specialist school.
Hamish continues not to allow achondroplasia to limit his childhood and has thrown himself into sporting activities, with his skiing skills particularly impressive. As Hamish nears his move to secondary school, he knows that his parents will continue to be a pillar of support.
