First broadcast: Monday 19 October 2009, 9PM on Channel 4
As experts consider a review of UK guidelines for treating transgender children, this film follows a number of children in the US who told their parents they were born in the wrong body.
First broadcast: Sunday 16 August 2009, 10PM on More4
Weighing the same as five baby elephants and a shade less than a Mini Cooper, Patrick Deuel is one of the heaviest men ever - and a medical miracle. His heart and other organs should have…
First broadcast: Thursday 11 June 2009, 9PM on Channel 4
In her home town of Nagpur in India, 16-year-old Jyoti Amge is a normal teenager in many ways: she enjoys going to school and socialising with friends, and dreams of dancing in Bollywood movies…
First broadcast: Sunday 01 February 2009, 10PM on More4
Half Ton Mum tells the story of the world's heaviest woman, Renee Williams, a 64-stone, 29-year-old mother of two who, in a desperate bid to lose enough weight to save her life, undergoes…
First broadcast: Monday 12 January 2009, 10PM on Channel 4
Nineteen-year-old Billy Robbins weighs 60 stone and is reported to be the world's heaviest teenager. He has spent the past three years living in a chair as his mother cooks for, cleans and feeds…
First broadcast: Wednesday 26 November 2008, 11.05PM on More4
At just seven years old Dzhambulat Khatokhov ('Jambik' for short) is four foot three inches tall and weighs 16 stone - as much as a baby elephant. He dwarfs his older brother who is twice his…
Manar Maged was born with two heads. The second has a brain, but no body. Despite this, the second head shows signs of independent consciousness - blinking, smiling, crying. It even tries to…
With her legs fused together like a tail, Milagros Cerron has one of the rarest birth abnormalities in the world: sirenomelia, or 'mermaid syndrome'. Can an operation by charismatic but…
China's 'Elephant Man', Huang Chuncai, tells his own shocking story as he undergoes surgery to remove life-threatening tumours weighing 20kg that have caused him a lifetime of suffering.
In the Romanian province of Transylvania, Lucica Bunghez is being eaten alive, consumed by an 11-stone tumour growing out of her back. Eventually, it will kill her.
A Swiss doctor discovered these tiny, fragile children in a remote Indian village in 2003. Their bones were dissolving and their hair thining and he diagnosed them with progeria, a rare disease…
The incredible story of seven-year-old Alamjan from Kazakhstan who underwent surgery for a distended stomach that was making him look pregnant. What the doctors discovered inside was reported…
For a few weeks in 2007 she was the most famous little girl in the world. Lakshmi Tatma was the girl with eight limbs, born with one of the world's rarest physical abnormalities.
On 9 March 2001, Armin Meiwes, a computer engineer from the tiny village of Wüstefeld in Germany, cut off the penis of Bernd Brandes, a software designer from Berlin.