US Secretary of State John Kerry has said a speech by Iran's supreme leader, who vowed to defy US policies despite a recent nuclear deal, was "very disturbing".
The most astonishing aspect of today's deal on Iran's nuclear capability is that neither side is negotiating the terms of its defeat.
President Barack Obama calls today's Iran nuclear agreement a "comprehensive deal", while President Rouhani says a "new chapter" has begun in his country's relations with the world.
After 12 years of talks, it seems Iran has agreed to scale back its nuclear programme in exchange for the lifting of UN sanctions that have crippled the country's economy.
A deal on Iran's nuclear programme would be a historic event - but it could come at the expense of angering some of the US's staunchest allies.
It has been a bad week for the American-led "strategy" against militants from so-called Islamic State - a strategy with the US president himself views with great qualms and some reluctance.
US Secretary of State John Kerry says he is "not going to step away from our alliances" in the Middle East, and was well aware of the support Iran was providing to Houthi rebels in Yemen.
Only those versed in Iranian political custom immediately understood the symbolism of a social call made by Iran's Supreme Leader Ayatollah Khamenei.
Unlike the US, the Iranians are not releasing fact sheets about the scale of nuclear reduction because they would rather be a little vague on the compromises they've made.