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"She smoked something. It's not marijuana but it is similar to incense. She seems to be having convulsions of some sort," a female friend of Moore told emergency services when calling for an ambulance on Monday, 23 January.
"She has been having some issues. I don't know what she has been taking," another woman at Moore's house that night said during the emergency call. Moore was also described as "burning up", unable to speak and semi-conscious before help arrived at her Beverly Hills mansion.
The tape shed the first official light on the emergency that sent recently separated Moore to the hospital, and later to seek treatment for what her spokeswoman has described only as "exhaustion".
Los Angeles officials said portions of the tape recording had been edited for privacy and to remove references to specific substances.
The actress, 49, filed for divorce from husband Ashton Kutcher, 33, in November after Kutcher had a widely publicized fling with another woman.
Her gaunt appearance in paparazzi photos over the last few months has raised alarm bells in the celebrity media.
Mr Moore's spokeswoman said on Tuesday that she had decided to seek professional treatment for "exhaustion and (to) improve her overall health" because of stress. Moore's representatives have declined to give any details or comment further on her problems.