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Chromosome 11 is a fictitious genetic case study where the social, ethical and medical aspects of an inherited disease are investigated as the user is guided through a mock genetic counselling session. After the case history and introduction, the user has to use his or her problem solving skills to piece together a family's medical history, with the clever use of clues a medical reference and other sources of information. Many core aspects of Key Stage 3 science are discussed and defined in a scientific and ethical context. This activity focuses on the outcomes of Mendelian inheritance, and how a gene for disease can pass through generations. The inheritance of diseases, the genes responsible for disease, and the techniques used to treat and identify them are highlighted whilst involving the user in the ethics of how knowledge of genetics affects people's lives, and how they live them. The following links provide further information on Sickle cell anaemia or genetic counselling: An explanation and video from American TV company PBS about sickle cell as a mutation and how it affects the population in malarial areas of Africa. The website of the American National Society of Genetic Counselors. British charity Sickle Cell Society offers "information, counselling and caring for those with Sickle Cell Disorders and their families". |
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Bug Lab  Chromosome 11 Lectures Royal Institution Credits |
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